UICC World Cancer Congress 2006
Bridging the Gap: Transforming Knowledge into Action
July 8-12, 2006, Washington, DC, USA
Sunday, 9 July 2006 - 12:00 PM
9-62
9-62
Usefulness of the Triple Test Score for Breast Lesions
Mehrdad Mokri, MD.Researcher., morteza atri, masoumeh guiti, and ali arab kherdmand. Cancer Institue., Shahid Beheshti University.Medical science., No 51-st zarnegar-st atlasi-st mirdamad-tehran-iran, Tehran, Iran
Objective:The triple test score (TTS) is useful and accurate for evaluating breast lesions.
Methods:This method was retrospective,during from1998 to 2003 ,6400 files were conveyed . 100 files had three main diagnostic features of this procedure, includes physical examination , mammography , FNA in association with postoperation pathology result . Three main diagnostic assigned a score of 1, 2 or 3 for benign, Suspicious or malignant results; the TTS is the sum of these scores. The TTS has a minimum score of 3 (concordant benign) and a maximum score of 9 (concordant malignant). The TTS was correlated with subsequent histopathologic analysis or follow-up.
Results: All lesions with TTS less than or equal to 4 were benign on clinical follow-up. Of the 23 lesions (23%) with score of 5,which considered as suspicious 6 (6%) were benign lesions, 17 (17%) were malignant lesions. All lesions with TTS greater than or equal to 6 were malignant on excisional biopsy . We resulted that in our setting, TTS less than or equal to 4 has a specificity of 100% and TTS greater than or equal to 6 has a sensitivity of 100%. If TTS is being used as a screening test the sensitivity = 96.7% & specificity = 78.9% & accuracy = 90% .The TTS reliably guides evaluation and treatment of breast lesions. Lesions scoring 3 or 4 are always benign. Lesions with scores greater than or equal to 6 are malignant and should be treated accordingly. Confirmatory biopsy is required only for 23% of the lesions that receive a TTS of 5.