Modified triple test score (MTTS) for the evaluation of palpable breast masses in women

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2007 AACR Annual Meeting
April 14-18, 2007
Los Angeles, CA
Abstract Number:3517
Presentation Title: Modified triple test score (MTTS) for the evaluation of palpable breast masses in women under age 40
Presentation Start/End Time:Tuesday, Apr 17, 2007, 8:00 AM -12:00 PM
Location:Exhibit Hall, Los Angeles Convention Center
Poster Section:7
Poster Board Number:8
Author Block:
Mehrdad Mokri, Masoumeh Guity, Siamak Shariat Torbaghan, Mostafa Bagerzade, John T. Vetto, Morteza Atri. Day General Hospital, Tehran, Iran (Islamic Republic of), Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), Oregon Health Science University, Portland, OR

Introduction: Evaluating the usefulness of Modified Triple Test Score (MTTS) in palpable breast masses in women under age 40.
Materials and Methods:
Medical records of 67 cases with the data of physical examination, ultrasonography and fine-needle aspiration cytology (FNAC) were evaluated and MTTS was calculated and correlated with post operation pathology result and fallow up. Results: Among 67 masses, 6 scored 3 points, 30 scored 4 points; 11 scored 5 points; 1 was malignant. 20 scored >or=6 points: all were malignant. Of the 11 masses with score of 5, which considered as suspicious 10 were benign masses, 1 was malignant mass. The MTTS has 100% diagnostic accuracy when other than 5 points. Masses scoring or=6 points may proceed to definitive therapy. Conclusions: The MTTS reliably guides evaluation and treatment of breastpalpable breast masses in women under age 40. MTTS 3 or 4 are always benign and with scores greater than or equal to 6 are malignant and should be treated accordingly. This approach avoids open biopsy in the majority of cases, while capturing all malignancies. The MTTS provides equivalent diagnostic effectiveness but substantially lower cost than traditional management


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